Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281

Author:

Liu Jinghan,Offei Samuel D.,Yoshimoto Francis K.ORCID,Scott Emily E.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference27 articles.

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2. Purification and characterization of 7alpha-hydroxy-4-cholesten-3-one 12alpha-hydroxylase;Ishida;J. Biol. Chem.,1992

3. Cholic acid aids absorption, biliary secretion, and phase transitions of cholesterol in murine cholelithogenesis;Wang;Am. J. Physiol.,1999

4. Cholic acid supplementation enhances cholesterol absorption in humans;Woollett;Gastroenterology,2004

5. Comparative effects of cholic, chenodeoxycholic, and ursodeoxycholic acids on micellar solubilization and intestinal absorption of cholesterol;Reynier;J. Lipid Res.,1981

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1. Cytochrome P450 enzymes as drug targets in human disease;Drug Metabolism and Disposition;2023-10-04

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