“Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation

Author:

Roper Barnaby W.R.ORCID,Tiede ChristianORCID,Abdul-Zani IzmaORCID,Cuthbert Gary A.,Jade Dhananjay,Al-Aufi Ahmed,Critchley William R.ORCID,Saikia Queen,Homer-Vanniasinkam Shervanthi,Sawamura Tatsuya,McPherson Michael J.,Harrison Michael A.,Tomlinson Darren C.,Ponnambalam Sreenivasan

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference69 articles.

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2. Oxidative modification of lipoproteins;Arai,2014

3. Oxidized low-density lipoprotein;Parthasarathy,2010

4. Modification of low-density lipoprotein by endothelial-cells involves lipid-peroxidation and degradation of low-density lipoprotein phospholipids;Steinbrecher;Proc. Natl. Acad. Sci. U. S. A.,1984

5. Evidence for a concerted reaction between lipid hydroperoxides and polypeptides;Fruebis;Proc. Natl. Acad. Sci. U. S. A.,1992

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