A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities-Reference-Cited by-同舟云学术

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A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities

Published:2023-09 Issue:9 Volume:299 Page:105072
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Soudah Nadine,Baskin Alexey,Smorodinsky-Atias Karin^ORCID,Beenstock Jonah,Ganon Yifat,Hayouka Ruchama,Aboraya Mohammed,Livnah Oded,Ilouz Ronit,Engelberg David

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference65 articles.

1. The protein kinase complement of the human genome;Manning;Science,2002

2. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1;Hanks;FASEB J.,1995

3. Evolution of the eukaryotic protein kinases as dynamic molecular switches;Taylor;Philosophical Trans. R. Soc. B: Biol. Sci.,2012

4. From structure to the dynamic regulation of a molecular switch: a journey over 3 decades;Taylor;J. Biol. Chem.,2021

5. How do protein kinases take a selfie (autophosphorylate)?;Beenstock;Trends Biochem. Sci.,2016

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1. ERK pathway agonism for cancer therapy: evidence, insights, and a target discovery framework;npj Precision Oncology;2024-03-14

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