Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference41 articles.
1. Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection;de Wit;Proc. Natl. Acad. Sci. U. S. A.,2020
2. Remdesivir for the treatment of Covid-19 - final report;Beigel;N. Engl. J. Med.,2020
3. The time to offer treatments for COVID-19;Ngo;Expert Opin. Invest. Drugs,2021
4. Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses;Artese;Drug Resist. Updat.,2020
5. Compassionate use of remdesivir for patients with severe Covid-19;Grein;N. Engl. J. Med.,2020
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