Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference74 articles.
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2. The biology of Lonp1: More than a mitochondrial protease;Gibellini;Int. Rev. Cell Mol. Biol.,2020
3. The mitochondrial Lon protease: Novel functions off the beaten track?;Voos;Biomolecules,2020
4. Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer;Quiros;Mol. Cell. Oncol.,2014
5. Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy;Nimmo;Hum. Mol. Genet.,2019
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