Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins
Author:
Funder
Biotechnology and Biological Sciences Research Council
Cancer Research UK
Wellcome Trust
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference42 articles.
1. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing;Ivan;Science,2001
2. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation;Jaakkola;Science,2001
3. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation;Epstein;Cell,2001
4. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway;Kaelin;Mol. Cell,2008
5. Molecular responses to hypoxia-inducible factor 1α and beyond;Brocato;Mol. Pharmacol.,2014
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Substrate selectivity and inhibition of the human lysyl hydroxylase JMJD7;Protein Science;2024-09-14
2. A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity;Angewandte Chemie International Edition;2024-07-31
3. A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity;Angewandte Chemie;2024-07-31
4. Hypoxia-inducible factors: details create a picture. Part I. HIF-1;Fundamental and Clinical Medicine;2023-09-29
5. Biochemical and Structural Insights into FIH‐Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains;ChemBioChem;2023-01-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3