Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition-Reference-Cited by-同舟云学术

Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition

Published:2024-01 Issue:1 Volume:300 Page:105492
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Bedard Gabriel T.,Gilaj Nord,Peregrina Karina,Brew Isabella,Tosti Elena,Shaffer Karl,Tyler Peter C.^ORCID,Edelmann Winfried,Augenlicht Leonard H.,Schramm Vern L.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference50 articles.

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4. MTAPdeletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells;Kryukov;Science,2016

5. A patent review of MAT2a inhibitors (2018–2021);Atkinson;Expert Opin. Ther. Pat.,2022

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