GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6-Reference-Cited by-同舟云学术

GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6

Published:2021-10 Issue:4 Volume:297 Page:101125
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Yang Pei-Lin,Li Xing-Hua,Wang Jin^ORCID,Ma Xue-Fei,Zhou Bo-Ying,Jiao Yuan-Feng,Wang Wen-Hui,Cao Peng,Zhu Michael Xi^ORCID,Li Pei-Wang,Xiao Zhi-Hong,Li Chang-Zhu,Guo Chang-Run,Lei Yun-Tao,Yu Ye

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference58 articles.

1. How TRPC channels modulate hippocampal function;Gualdani;Int. J. Mol. Sci.,2020

2. Role of TRPC3 and TRPC6 channels in the myocardial response to stretch: Linking physiology and pathophysiology;Yamaguchi;Prog. Biophys. Mol. Biol.,2017

3. Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway;Mori;Front. Pharmacol.,2015

4. Brain-derived neurotrophic factor regulates TRPC3/6 channels and protects against myocardial infarction in rodents;Hang;Int. J. Biol. Sci.,2015

5. Store-operated Ca2+ entry mediated by Orai1 and TRPC1 participates to insulin secretion in rat β-cells;Sabourin;J. Biol. Chem.,2015

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2. Calcium transport and sensing in TRPC channels – New insights into a complex feedback regulation;Cell Calcium;2023-12

3. Selective Activation of a TRPC6 Ion Channel Over TRPC3 by Metalated Type-B Polycyclic Polyprenylated Acylphloroglucinols;Journal of Medicinal Chemistry;2023-11-03

4. Modulation and Regulation of Canonical Transient Receptor Potential 3 (TRPC3) Channels;Cells;2023-09-05

5. Transient Receptor Potential Canonical 6 (TRPC6) Channel in the Pathogenesis of Diseases: A Jack of Many Trades;Inflammation;2023-04-18