The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens
Author:
Funder
Canadian Institutes of Health Research
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference56 articles.
1. The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens;Hall;Endocrinology,1999
2. Dominant activity of activation function 1 (AF-1) and differential stoichiometric requirements for AF-1 and -2 in the estrogen receptor alpha-beta heterodimeric complex;Tremblay;Mol. Cell Biol.,1999
3. The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen;Zwart;J. Cell Sci.,2010
4. Estrogen receptor alpha and beta in health and disease;Jia;Best Pract. Res. Clin. Endocrinol. Metab.,2015
5. Coregulator function: a key to understanding tissue specificity of selective receptor modulators;Smith;Endocr. Rev.,2004
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Selective Estrogen Receptor Degraders (SERDs);Current Breast Cancer Reports;2024-07-26
2. Antagonism of Estrogen Receptor α-Driven Transcription Mediated by AP-1 in Breast Cancer Therapy;Endocrines;2024-03-06
3. Oral SERD, a Novel Endocrine Therapy for Estrogen Receptor-Positive Breast Cancer;Cancers;2024-01-31
4. Structural determinants of pure antiestrogenicity;2023-11-02
5. Estrogen Receptor Signaling in Breast Cancer;Cancers;2023-09-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3