Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860)-Reference-Cited by-同舟云学术

Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860)

Published:2004-11 Issue:6 Volume:18 Page:336-342
ISSN:1056-8727
Container-title:Journal of Diabetes and its Complications
language:en
Short-container-title:Journal of Diabetes and its Complications

Author:

Asano Tomoichiro,Saito Yasushi,Kawakami Masanobu,Yamada Nobuhiro,Sekino Hisakuni,Hasegawa Setsuo

Publisher

Elsevier BV

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference22 articles.

1. Fidarestat (SNK-860), a potent aldose reductase inhibitor, normalizes the elevated sorbitol accumulation in erythrocytes of diabetic patients;Asano;Journal of Diabetes and Its Complications,2002

2. Hyperglycemia, polyol metabolism, and complications of diabetes mellitus;Gabbay;Annual Review of Medicine,1975

3. Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes;Gabbay;Science,1966

4. Crucial role of aldose reductase activity and plasma glucose level in sorbitol accumulation in erythrocytes from diabetic patients;Hamada;Diabetes,1991

5. Aldose reductase-deficient mice are alleviated from the depletion of GSH in the peripheral nerve and MNCV deficit associated with diabetes;Ho;Diabetes,2001

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