Real-world evaluation of bebtelovimab effectiveness during the period of COVID-19 Omicron variants, including BA.4/BA.5

Author:

Molina Kyle C.,Kennerley Victoria,Beaty Laurel E.ORCID,Bennett Tellen D.,Carlson Nichole E.,Mayer David A.,Peers Jennifer L.,Russell SethORCID,Wynia Matthew K.ORCID,Aggarwal Neil R.ORCID,Ginde Adit A.

Publisher

Elsevier BV

Subject

Infectious Diseases,Microbiology (medical),General Medicine

Reference19 articles.

1. The impact of neutralizing monoclonal antibodies on the outcomes of COVID-19 outpatients: a systematic review and meta-analysis of randomized controlled trials;Lin;J Med Virol,2022

2. UD Food and Drug Administration. FDA updates Sotrovimab emergency use authorization, https://www.fda.gov/drugs/drug-safety-and-availability/fda-updates-sotrovimab-emergency-use-authorization; 2022 [accessed 08 November 2022].

3. Change in effectiveness of sotrovimab for preventing hospitalization and mortality for at-risk COVID-19 outpatients during an omicron BA.1 and BA.1.1-predominant phase;Aggarwal;Int J Infect Dis,2022

4. Augmented neutralisation resistance of emerging omicron subvariants BA.2.12.1, BA.4, and BA.5;Arora;Lancet Infect Dis,2022

5. Dougan M, Azizad M, Chen P, et al. Bebtelovimab, alone or together with bamlanivimab and etesevimab, as a broadly neutralizing monoclonal antibody treatment for mild to moderate, ambulatory COVID-19. medRxiv. 12 November 2022. https://www.medrxiv.org/content/10.1101/2022.03.10.22272100v1 [accessed 15 January 2023].

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