Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are needed

Author:

Hasford J.,Bramlage P.,Koch G.,Lehmacher W.,Einhäupl K.,Rothwell P.M.

Publisher

Elsevier BV

Subject

Epidemiology

Reference18 articles.

1. Why do we need some large, simple randomized trials?;Yusuf;Stat Med,1984

2. External validity of randomised controlled trials: “to whom do the results of this trial apply?”;Rothwell;Lancet,2005

3. Treating individuals 2. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation;Rothwell;Lancet,2005

4. IQWiG. Final report plan for the evaluation: “clopidogrel versus acetyl salicylic acid in the secondary prevention of vascular events”. 2006. Available at: http://www.iqwig.de/download/A04-1A_Abschlussbericht_Clopidogrel_versus_ASS_in_der_Sekundaerprophylaxe.pdf. Accessed January 21, 2008.

5. NICE. Clopidogrel and modified-release dipyridamole in the prevention of occlusive vascular events. 2005. Available at: http://www.nice.org.uk/nicemedia/pdf/TA090guidance.pdf. Accessed January 21, 2008.

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