Diverse Resistant Mechanisms Identified Using Serial Next-Generation Sequencing in a Patient With ALK-Rearranged Metastatic Lung Adenocarcinoma: A Case Report
Author:
Publisher
Elsevier BV
Subject
Pulmonary and Respiratory Medicine,Oncology
Reference8 articles.
1. Natural history and factors associated with overall survival in Stage IV ALK-rearranged non–small cell lung cancer;Pacheco;J Thorac Oncol,2019
2. Retrospective real-world outcomes for patients with ALK-rearranged lung cancer receiving ALK receptor tyrosine kinase inhibitors;Gibson;JTO Clin Res Rep,2021
3. First-line lorlatinib or crizotinib in advanced ALK-positive lung cancer;Shaw;N Engl J Med,2020
4. Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: incremental yield of actionable alterations and cost-effectiveness analysis;Tan;Lung Cancer,2020
5. I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib;Ou;Lung Cancer,2015
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