Insertion of interleukin-2 (IL-2) and interleukin-12 (IL-12) genes into vaccinia virus results in effective anti-tumor responses without toxicity-Reference-Cited by-同舟云学术

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Insertion of interleukin-2 (IL-2) and interleukin-12 (IL-12) genes into vaccinia virus results in effective anti-tumor responses without toxicity

Published:2002-03 Issue:13-14 Volume:20 Page:1862-1869
ISSN:0264-410X
Container-title:Vaccine
language:en
Short-container-title:Vaccine

Author:

Kaufman Howard L,Flanagan Ken,Lee Christopher S.D,Perretta Donato J,Horig Heidi

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference42 articles.

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2. Tumor antigens recognized by T cells;Boon;Immunol. Today,1997

3. Results of a phase I clinical trial using a recombinant vaccinia-carcinoembryonic antigen (CEA) vaccine in patients with advanced colorectal cancer;McAneny;Ann. Surg. Oncol.,1996

4. Replication-restricted vaccinia as a cytokine gene therapy vector in cancer: persistent transgene expression despite antibody generation;Mukherjee;Cancer Gene. Ther.,2000

5. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses;Marshall;J. Clin. Oncol.,2000

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