Update on the clinical development of gefapixant, a P2X3 receptor antagonist for the treatment of refractory chronic cough-Reference-Cited by-同舟云学术

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Update on the clinical development of gefapixant, a P2X3 receptor antagonist for the treatment of refractory chronic cough

Published:2019-06 Issue: Volume:56 Page:75-78
ISSN:1094-5539
Container-title:Pulmonary Pharmacology & Therapeutics
language:en
Short-container-title:Pulmonary Pharmacology & Therapeutics

Author:

Muccino David,Green Stuart

Funder

Merck Sharp & Dohme Corp.

Merck & Co., Inc.

Publisher

Elsevier BV

Subject

Pharmacology (medical),Biochemistry, medical,Pulmonary and Respiratory Medicine

Reference34 articles.

1. Classification of cough as a symptom in adults and management algorithms: CHEST guideline and expert panel report;Irwin;Chest,2018

2. The global epidemiology of chronic cough in adults: A systematic review and meta-analysis;Song;Eur. Respir. J.,2015

3. Change in psychological, physiological, and situational factors in adults after treatment of chronic cough;French;Chest,2017

4. Chronic cough from the patient's perspective;Kuzniar;Mayo Clin. Proc.,2007

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1. Druggable site near the upper vestibule determines the high affinity and P2X3 homotrimer selectivity of sivopixant/S‐600918 and its analogue DDTPA;British Journal of Pharmacology;2023-12-07

2. TO MARKET, TO MARKET–2022: SMALL MOLECULES;Medicinal Chemistry Reviews;2023-11-16

3. Chronic cough relief by allosteric modulation of P2X3 without taste disturbance;Nature Communications;2023-09-20

4. Gefapixant;pharma-kritik;2023-02-17

5. Risk Factors for Persistent Chronic Cough During Consecutive Years: A Retrospective Database Analysis;The Journal of Allergy and Clinical Immunology: In Practice;2022-06

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