Two-start design within a Sephadex inflammatory model – A means to generate reliable ED50 data whilst significantly reducing the number of animals used

Author:

Siller Helena,Taylor John D.,Middleton Brian

Publisher

Elsevier BV

Subject

Pharmacology (medical),Biochemistry, medical,Pulmonary and Respiratory Medicine

Reference24 articles.

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3. Rat models of asthma and chronic obstructive lung disease;Martin;Pulm Pharmacol Ther,2006

4. Isomaltitol exacerbates neutrophilia but reduces eosinophilia: new insights into the Sephadex model of lung inflammation;Evaldsson;Int Arch Allergy Immunol,2010

5. Eotaxin expression in Sephadex-induced lung injury in rats;Guo;Am J Pathol,1999

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