Analytical Challenges Assessing Protein Aggregation and Fragmentation Under Physiologic Conditions-Reference-Cited by-同舟云学术

Analytical Challenges Assessing Protein Aggregation and Fragmentation Under Physiologic Conditions

Published:2021-09 Issue:9 Volume:110 Page:3103-3110
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Schuster Joachim,Mahler Hanns-Christian,Joerg Susanne,Huwyler Joerg,Mathaes Roman

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference91 articles.

1. Chemical and physical instabilities in manufacturing and storage of therapeutic proteins;Krause;Curr Opin Biotechnol,2019

2. Postproduction handling and administration of protein pharmaceuticals and potential instability issues;Nejadnik;J Pharm Sci,2018

3. Vivo stability of therapeutic proteins;Schuster;Pharm Res,2020

4. Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditions;Schmid;Nature Commun Biol,2018

5. Quantitation and pharmacokinetic modeling of therapeutic antibody quality attributes in human studies;Li;MAbs,2016

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