Pharmacokinetic and Pharmacodynamic Evaluation of Different PEGylated Human Interleukin-11 Preparations in Animal Models

Author:

Yu Kuo-Ming,Yiu-Nam Lau Johnson,Fok Manson,Yeung Yuk-Keung,Fok Siu-Ping,Hu Tsan-Lin,Tsai Yuan-Jang,Choo Qui-Lim

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference28 articles.

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2. FDA-approved poly(ethylene glycol)-protein conjugate drugs;Alconcel;Polym Chem,2011

3. G. Cox-III, inventor, Bolder Biotechnology Inc., assignee. Cysteine Variants of Interleukin-11. US patent 8,133,480, 2012.

4. Y. Jung, S.-H. Ho, M.-O. Park, M.-S. Kim, inventors. Biopolymer Conjugates Comprising an Interleukin-11 Analog. US patent application 20100098658, 2010.

5. Enhanced pharmacological activity of recombinant human interleukin-11 (rhIL11) by chemical modification with polyethylene glycol;Takagi;J Control Release,2007

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