Noninvasive Moisture Detection in Lyophilized Drug Product Using NIR Spectrometer and Headspace Moisture Analyzer

Author:

Pu Yu-ElaineORCID,Li Ying,Xiang Dong

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference24 articles.

1. Ma, J. C. Regulatory control of freeze-dried products: importance and evaluation of residual moisture. In: Freeze Drying/Lyophilization of Pharmaceutical and Biological Products, 3rd ed. May, L. R. A. J. C., Ed. Informa Healthcare: 2010;206:288–316.

2. Headspace moisture analysis for determination of residual moisture content in lyophilized pharmaceutical products;Duncan;Pharmaceut Technol,2016

3. Near-infrared spectroscopic determination of residual moisture in lyophilized sucrose through intact glass vials;Kamat;Pharm Res,1989

4. Development and transferability of near-infrared methods for determination of moisture in a freeze-dried injection product;Jones;J Pharm Biomed Anal,1993

5. Applications of headspace moisture analysis for investigating the water dynamics within a sealed vial containing freeze-dried material;Cook;PDA J Pharm Sci Technol,2011

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