The Degradation Chemistry of Prasugrel Hydrochloride: Part 1—Drug Substance

Author:

Baertschi Steven W.,Maxwell-Backer Lindsay,Clemens Matthew,Smitka Tim A.,Draper Jerry R.,Taylor K. Wayne,Kaerner Andreas,Jansen Patrick J.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference32 articles.

1. Stereoselective metabolism of prasugrel in humans using a novel chiral liquid chromatography-tandem mass spectrometry method;Wickremsinhe;Drug Metab Dispos,2007

2. Determination of the active and inactive metabolites of prasugrel in human plasma by liquid chromatography/tandem mass spectrometry;Farid;Rapid Commun Mass Spectrom,2007

3. Disposition and metabolic fate of prasugrel in mice, rats, and dogs;Smith;Xenobiotica,2007

4. “Stability Testing of New Drug Substances and Products,” Q1A(R2),2003

5. Study of the forced degradation behavior of prasugrel hydrochloride by liquid chromatography with mass spectrometry and liquid chromatography with NMR detection and prediction of the toxicity of the characterized degradation products;Singh;J Sep Sci,2015

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