Biophysical Characterization and Stability of Modified IgG1 Antibodies with Different Hexamerization Propensities

Author:

van Kampen Muriel D.ORCID,Kuipers-De Wilt Leonie H.A.M.,van Egmond Mariëlle L.,Reinders-Blankert Petra,van den Bremer Ewald T.J.ORCID,Wang GuanboORCID,Heck Albert J.R.ORCID,Parren Paul W.H.I.,Beurskens Frank J.,Schuurman JanineORCID,de Jong Rob N.ORCID

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference53 articles.

1. Antibody structure and function: the basis for engineering therapeutics;Chiu;Antibodies (Basel),2019

2. IgG Fc engineering to modulate antibody effector functions;Wang;Protein Cell,2018

3. Bispecific antibodies: a mechanistic review of the pipeline;Labrijn;Nat Rev Drug Discov,2019

4. Antibody-mediated complement activation in pathology and protection;Goldberg;Immunol Cell Biol,2020

5. Multiple variables at the leukocyte cell surface impact Fc gamma receptor-dependent mechanisms;Patel;Front Immunol,2019

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