How to Evaluate If Microorganisms Isolated From Sterile Drug Production Environments Monitoring Are Undesirable

Author:

Ceccanti Stefano,Vecchiani Sandra,Leonangeli Giulia,Burgalassi Susi,Federigi IleanaORCID,Carducci Annalaura,Verani Marco

Publisher

Elsevier BV

Reference27 articles.

1. European Union. Commission Directive 2003/94/EC of 8 October 2003 laying down the principles and guidelines of good manufacturing practice in respect of medicinal products for human use and investigational medicinal products for human use. Available at: https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32003L0094 (last accessed on 22 November 2023).

2. Eudralex. The Rules Governing Medicinal Products in the European Union,Volume 4: Good Manufacturing Practice for Medicinal Products for Human and Veterinary use, Annex 1- Manufacture of sterile medicinal products,2022

3. Sutton S. Understand your facility's microflora. In: Madsen RE, Moldenhauer J, eds. Contamination control in healthcare product manufacturing, Vol. 1. PDA/DHI: Bethesda, MD, 2014; pp 17-19

4. What is an objectionable MO?;Sutton;Am. Pharm. Rev,2012

5. Technical Report no 13. Fundamentals of Environmental Monitoring Program,2022

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