Cis/Trans Isomerization of Unsaturated Fatty Acids in Polysorbate 80 During Light Exposure of a Monoclonal Antibody–Containing Formulation-Reference-Cited by-同舟云学术

Cis/Trans Isomerization of Unsaturated Fatty Acids in Polysorbate 80 During Light Exposure of a Monoclonal Antibody–Containing Formulation

Published:2020-01 Issue:1 Volume:109 Page:603-613
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Prajapati Indira,Peters Björn-Hendrik,Larson Nicholas R.,Wei Yangjie,Choudhary Sureshkumar,Kalonia Cavan,Hudak Suzanne,Esfandiary Reza,Middaugh C. Russell,Schöneich Christian

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference50 articles.

1. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways;Kerwin;J Pharm Sci,2008

2. Considerations for the use of polysorbates in biopharmaceuticals;Jones;Pharm Res,2018

3. Polysorbate degradation in biotherapeutic formulations: identification and discussion of current root causes;Dwivedi;Int J Pharm,2018

4. Effect of polysorbate 80 quality on photostability of a monoclonal antibody;Singh;AAPS PharmSciTech,2012

5. Peroxide formation in polysorbate 80 and protein stability;Ha;J Pharm Sci,2002

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Visible light triggers the formation of reactive oxygen species in monoclonal antibody formulations;International Journal of Pharmaceutics;2024-08

2. Bioactive pH-sensitive nanoemulsion in melanoma cell lines;International Journal of Pharmaceutics;2024-08

3. Protein photodegradation in the visible range? Insights into protein photooxidation with respect to protein concentration;International Journal of Pharmaceutics: X;2023-12

4. Oxidation of polysorbates – An underestimated degradation pathway?;International Journal of Pharmaceutics: X;2023-12

5. Development of UPLC-UV-ELSD Method for Fatty Acid Profiling in Polysorbate 80 and Confirmation of the Presence of Conjugated Fatty Acids by Mass Spectrometry, UV Absorbance and Proton Nuclear Magnetic Resonance Spectroscopy;Journal of Pharmaceutical Sciences;2023-09