Dynamic and Static Simulations of Fluvoxamine-Perpetrated Drug-Drug Interactions Using Multiple Cytochrome P450 Inhibition Modeling, and Determination of Perpetrator-Specific CYP Isoform Inhibition Constants and Fractional CYP Isoform Contributions to Victim Clearance
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Published:2016-03
Issue:3
Volume:105
Page:1307-1317
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ISSN:0022-3549
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Container-title:Journal of Pharmaceutical Sciences
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language:en
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Short-container-title:Journal of Pharmaceutical Sciences
Subject
Pharmaceutical Science
Cited by
9 articles.
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1. Interplay of UDP-Glucuronosyltransferase and CYP2C8 for CYP2C8 Mediated Drug Oxidation and Its Impact on Drug–Drug Interaction Produced by Standardized CYP2C8 Inhibitors, Clopidogrel and Gemfibrozil;Clinical Pharmacokinetics;2023-11-03
2. Pharmacokinetic and Pharmacodynamic Drug–Drug Interactions: Research Methods and Applications;Metabolites;2023-07-29
3. Comparative analysis of CYP2C8-medidated drug-drug interactions produced by CYP2C8 inhibitors, gemfibrozil versus clopidogrel, focusing on the inhibition of drug distribution in UDP-glucuronosyltransferase prior to oxidation;2023-01-09
4. Disease-drug and drug-drug interaction in COVID-19: Risk and assessment;Biomedicine & Pharmacotherapy;2021-07
5. A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug–Drug–Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine;Pharmaceutics;2020-12-08