Understanding the Interplay Between Uptake and Efflux Transporters Within In Vitro Systems in Defining Hepatocellular Drug Concentrations
Author:
Funder
GlaxoSmithKline
Janssen
Lilly
Pfizer
University of Manchester
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference61 articles.
1. Transporters as a determinant of drug clearance and tissue distribution;Shitara;Eur J Pharm Sci,2006
2. The roles of transporters and enzymes in hepatic drug processing;Liu;Drug Metab Dispos,2005
3. Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide;Ishiguro;Drug Metab Dispos,2008
4. Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin;Kitamura;Drug Metab Dispos,2008
5. Prediction of human metabolic clearance from in vitro systems: retrospective analysis and prospective view;Hallifax;Pharm Res,2010
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