The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR-Reference-Cited by-同舟云学术

The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR

Published:2002-06 Issue:5 Volume:28 Page:875-885
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Tugnait M,Lenz E.M,Phillips P,Hofmann M,Spraul M,Lindon J.C,Nicholson J.K,Wilson I.D

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference15 articles.

1. The Primary Aromatic Amines: Their Biological Properties and Structure-Activity Relationships

2. Oxidation of acetanilides to glycolanilides and oxanilic acids in rabbits

3. Hydroxylation of N-(4-chlorophenyl)[14C1]acetamide to N-(4-chlorophenyl)-[14C1]glycolamide in rabbits

4. Metabolites of 4-chloroaniline and chloroacetanilides produced by rabbits and pigs

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