Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients
Author:
Funder
Gilead Sciences
Publisher
Elsevier BV
Subject
Cell Biology,Endocrinology,Biochemistry
Reference31 articles.
1. Fatty acid synthase and liver triglyceride metabolism: housekeeper or messenger?;Jensen-Urstad;Biochim. Biophys. Acta Mol. Cell Biol. Lipids,2012
2. Regulation of hepatic de novo lipogenesis in humans;Hellerstein;Annu. Rev. Nutr.,1996
3. Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease;Lambert;Gastroenterology (New York, N.Y. 1943),2014
4. Acetyl-CoA carboxylase inhibitor GS-0976 for 12 weeks reduces hepatic de novo lipogenesis and steatosis in patients with nonalcoholic steatohepatitis;Lawitz;Clin. Gastroenterol. Hepatol.,2018
5. Acetyl CoA carboxylase inhibition reduces hepatic steatosis but elevates plasma triglycerides in mice and humans: a bedside to bench investigation;Kim;Cell Metab.,2017
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