TGF-β Inhibition Improves Oncolytic Herpes Viroimmunotherapy in Murine Models of Rhabdomyosarcoma-Reference-Cited by-同舟云学术

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TGF-β Inhibition Improves Oncolytic Herpes Viroimmunotherapy in Murine Models of Rhabdomyosarcoma

Published:2017-12 Issue: Volume:7 Page:17-26
ISSN:2372-7705
Container-title:Molecular Therapy - Oncolytics
language:en
Short-container-title:Molecular Therapy - Oncolytics

Author:

Hutzen Brian,Chen Chun-Yu,Wang Pin-Yi,Sprague Les,Swain Hayley M.,Love Julia,Conner Joe,Boon Louis,Cripe Timothy P.

Funder

Research Institute at Nationwide Children’s Hospital

Publisher

Elsevier BV

Subject

Pharmacology (medical),Cancer Research,Oncology,Molecular Medicine

Reference37 articles.

1. Declining childhood and adolescent cancer mortality;Smith;Cancer,2014

2. Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity;Leddon;Mol Ther Oncolytics,2015

3. Widespread intratumoral virus distribution with fractionated injection enables local control of large human rhabdomyosarcoma xenografts by oncolytic herpes simplex viruses;Currier;Cancer Gene Ther.,2005

4. VEGF blockade decreases the tumor uptake of systemic oncolytic herpes virus but enhances therapeutic efficacy when given after virotherapy;Eshun;Gene Ther.,2010

5. Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide;Currier;Mol. Ther.,2008

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1. Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors;Frontiers in Immunology;2024-06-25

2. The combination therapy of oncolytic virotherapy;Frontiers in Pharmacology;2024-04-25

3. Integrating innate and adaptive immunity in oncolytic virus therapy;Trends in Cancer;2023-10

4. An oncolytic virus–delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment;Journal of Experimental Medicine;2023-08-08

5. Oncolytic virotherapy: basic principles, recent advances and future directions;Signal Transduction and Targeted Therapy;2023-04-11

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