A cross-reactive pH-dependent EGFR antibody with improved tumor selectivity and penetration obtained by structure-guided engineering
Author:
Funder
Ministry of Science and Technology of the People's Republic of China
Publisher
Elsevier BV
Subject
Pharmacology (medical),Cancer Research,Oncology,Molecular Medicine
Reference67 articles.
1. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells;Ullrich;Nature,1984
2. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains;Ogiso;Cell,2002
3. EGF receptor ligands;Harris;Exp. Cell Res.,2003
4. EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics;Freed;Cell,2017
5. EGFR family: structure physiology signalling and therapeutic targets;Burgess;Growth Factors,2008
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