MicroRNA-detargeting proves more effective than leader gene deletion for improving safety of oncolytic Mengovirus in a nude mouse model
Author:
Funder
Mayo Clinic
National Institutes of Health
National Cancer Institute
Publisher
Elsevier BV
Subject
Pharmacology (medical),Cancer Research,Oncology,Molecular Medicine
Reference70 articles.
1. MicroRNAs and oncolytic viruses;Ruiz;Curr. Opin. Virol.,2015
2. MicroRNAs fine-tune oncolytic viruses;Bell;Nat. Biotechnol.,2008
3. MicroRNA regulation of oncolytic herpes simplex virus-1 for selective killing of prostate cancer cells;Lee;Clin. Cancer Res.,2009
4. MicroRNA regulation of glycoprotein B5R in oncolytic vaccinia virus reduces viral pathogenicity without impairing its antitumor efficacy;Hikichi;Mol. Ther.,2011
5. Construction of an oncolytic herpes simplex virus that precisely targets hepatocellular carcinoma cells;Fu;Mol. Ther.,2012
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Microglia-specific IL-10 gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson’s disease;Science Translational Medicine;2024-08-21
2. miRNA-Mediated Mechanisms in the Generation of Effective and Safe Oncolytic Viruses;Pharmaceutics;2024-07-25
3. Tutorial: design, production and testing of oncolytic viruses for cancer immunotherapy;Nature Protocols;2024-05-20
4. Polycytidine tract deletion from microRNA-detargeted oncolytic Mengovirus optimizes the therapeutic index in a murine multiple myeloma model;Molecular Therapy - Oncolytics;2023-03
5. Immunology Meets Bioengineering: Improving the Effectiveness of Glioblastoma Immunotherapy;Cancers;2022-07-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3