Biotransformation of prednisone and dexamethasone by cytochrome P450 based systems – Identification of new potential drug candidates

Author:

Putkaradze Natalia,Kiss Flora Marta,Schmitz Daniela,Zapp Josef,Hutter Michael C.,Bernhardt Rita

Funder

Birgit Heider-Lips for the purification of AdR and Adx4-108 and Dr

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference39 articles.

1. Studies on the substrate specificity and inducibility of cytochrome P-450meg;Berg;Biochem. J.,1981

2. Characterization of a cytochrome P-450-dependent steroid hydroxylase system present in Bacillus megaterium;Berg;J. Biol. Chem.,1976

3. Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations;Bernhardt;Appl. Microbiol. Biotechnol.,2014

4. Cytochromes P450 as versatile biocatalysts;Bernhardt;J. Biotechnol.,2006

5. A new Bacillus megaterium whole-cell catalyst for the hydroxylation of the pentacyclic triterpene 11-keto-β-boswellic acid (KBA) based on a recombinant cytochrome P450 system;Bleif;Appl. Microbiol. Biotechnol.,2011

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