Antibody engineering of a cytotoxic monoclonal antibody 84 against human embryonic stem cells: Investigating the effects of multivalency on cytotoxicity-Reference-Cited by-同舟云学术

Antibody engineering of a cytotoxic monoclonal antibody 84 against human embryonic stem cells: Investigating the effects of multivalency on cytotoxicity

Published:2017-02 Issue: Volume:243 Page:29-37
ISSN:0168-1656
Container-title:Journal of Biotechnology
language:en
Short-container-title:Journal of Biotechnology

Author:

Klement Maximilian,Zheng Jiyun,Liu Chengcheng,Tan Heng-Liang,Wong Victor Vai Tak,Choo Andre Boon-Hwa,Lee Dong-Yup,Ow Dave Siak-Wei

Funder

Agency for Science, Technology and Research (A*STAR) Joint Council Office Grant

National Research Foundation of Singapore

Biomedical Research Council of A*STAR

Next-Generation BioGreen 21 Program

Rural Development Administration, Republic of Korea

National University of Singapore

A*STAR Graduate Academy (A*GA), Singapore

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference43 articles.

1. Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen;Ben-David;Cell Stem Cell,2013

2. The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells;Blum;Nat. Biotechnol.,2009

3. The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility;Carmichael;J. Mol. Biol.,2003

4. Tumour targeting of humanised cross-linked divalent-Fab' antibody fragments: a clinical phase I/II study;Casey;Br. J. Cancer,2002

5. Therapeutic antibody fragments with prolonged in vivo half-lives;Chapman;Nat. Biotechnol.,1999

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Multivalent protein-drug conjugates – An emerging strategy for the upgraded precision and efficiency of drug delivery to cancer cells;Biotechnology Advances;2023-10

2. Live long and active: Polypeptide-mediated assembly of antibody variable fragments;Advanced Drug Delivery Reviews;2020-12

3. Immunoliposomes in clinical oncology: State of the art and future perspectives;Journal of Controlled Release;2018-04