Control of IgG LC:HC ratio in stably transfected CHO cells and study of the impact on expression, aggregation, glycosylation and conformational stability

Author:

Ho Steven C.L.,Koh Esther Y.C.,van Beers Miranda,Mueller Monika,Wan Corrine,Teo Gavin,Song Zhiwei,Tong Yen Wah,Bardor Muriel,Yang Yuansheng

Funder

Biomedical Research Council/Science and Engineering Research Council of A*STAR (Agency for Science, Technology and Research)

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference47 articles.

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4. Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by mammalian cell systems;Butler;Cytotechnology,2006

5. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?;Chusainow;Biotechnology and Bioengineering,2009

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