Effect of linker flexibility and length on the functionality of a cytotoxic engineered antibody fragment-Reference-Cited by-同舟云学术

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Effect of linker flexibility and length on the functionality of a cytotoxic engineered antibody fragment

Published:2015-04 Issue: Volume:199 Page:90-97
ISSN:0168-1656
Container-title:Journal of Biotechnology
language:en
Short-container-title:Journal of Biotechnology

Author:

Klement Maximilian,Liu Chengcheng,Loo Bernard Liat Wen,Choo Andre Boon-Hwa,Ow Dave Siak-Wei^ORCID,Lee Dong-Yup^ORCID

Funder

National University of Singapore

Biomedical Research Council of A*STAR (Agency for Science, Technology and Research)

A*STAR Graduate Academy (A*GA), Singapore

Next-Generation BioGreen 21 Program

Rural Development Administration, Republic of Korea

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference26 articles.

1. Discovery Studio Modeling Environment, Release 2.5;Accelrys Software Inc.,2013

2. Antibody constructs in cancer therapy: protein engineering strategies to improve exposure in solid tumors;Beckman;Cancer,2007

3. GROMACS: a message-passing parallel molecular dynamics implementation;Berendsen;Comput. Phys. Commun.,1995

4. Fusion protein linkers: property, design and functionality;Chen;Adv. Drug Deliv. Rev.,2013

5. Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1;Choo;Stem Cells (Dayton, Ohio),2008

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