State variables monitoring by in situ multi-wavelength fluorescence spectroscopy in heterologous protein production by Pichia pastoris

Author:

Surribas Anna,Geissler David,Gierse Alexander,Scheper Thomas,Hitzmann Bernd,Montesinos José Luis,Valero Francisco

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference24 articles.

1. Chemometric modeling with two-dimensional fluorescence data for Claviceps purpurea bioprocess characterization;Boehl;J. Biotechnol.,2003

2. Bro, R., 1998. Multi-way analysis in the food industry; models, algorithms and applications, PhD. Royal Veterinary and Agricultural University, KVL Frederiksberg, Denmark.

3. Comparative production of human interleukin-2 fused with green fluorescent protein in several recombinant expression systems;Cha;Biochem. Eng. J.,2005

4. On-line fluorescence spectroscopy and chemometrics for qualitative and quantitative analysis: application in the sugar industry;Christensen;Spectrosc. Eur.,1999

5. Combined effect of the methanol utilization (Mut) phenotype and gene dosage on recombinant protein production in Pichia pastoris fed-batch cultures;Cos;J. Biotechnol.,2005

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