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Rational engineering of enzyme stability

Published:2004-09 Issue:1-3 Volume:113 Page:105-120
ISSN:0168-1656
Container-title:Journal of Biotechnology
language:en
Short-container-title:Journal of Biotechnology

Author:

Eijsink Vincent G.H.,Bjørk Alexandra,Gåseidnes Sigrid,Sirevåg Reidun,Synstad Bjørnar,Burg Bertus van den,Vriend Gert

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference145 articles.

1. Hydrophobic core repacking and aromatic–aromatic interaction in the thermostable mutant of T4 lysozyme Ser117 → Phe.;Anderson;Protein Sci.,1993

2. Enzyme engineering reaches the boiling point;Arnold;Proc. Natl. Acad. Sci. USA,1998

3. How enzymes adapt: lessons from directed evolution;Arnold;Trends Biochem. Sci.,2001

4. Thermostability and thermoactivity of citrate synthases from the thermophilic and hyperthermophilic archaea Thermoplasma acidophilum and Pyrococcus furiosus;Arnott;J. Mol. Biol.,2000

5. Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer–dimer interface;Bjørk;J. Mol. Biol.,2003

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