Investigation into the use of gamma irradiated Cytodex-1 microcarriers to produce a human cytomegalovirus (HCMV) vaccine candidate in epithelial cells

Author:

Spatafore Daniel,Warakomski Donald,Hofmann Carl,Christanti Sianny,Wagner James M.

Funder

Merck Sharp and Dohme

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference35 articles.

1. Phase 1 clinical trial of a conditionally replication-defective human cytomegalovirus (CMV) vaccine in CMV-seronegative subjects;Adler;J. Infect. Dis.,2019

2. Production of Newcastle disease virus by Vero cells grown on cytodex 1 microcarriers in a 2-litre stirred tank bioreactor;Arifin;J. Biomed. Biotechnol.,2010

3. Risk analysis of leachables in cell and gene therapy using a CAR-T model process;Budde;Int J. Pharm.,2021

4. CDC. Cytomegalovirus (CMV) and Congenital CMV Infection. 18Aug2020 25Jan2022]; Available from: 〈https://www.cdc.gov/cmv/index.html〉.

5. Cytodex 1 Gamma Validation Guide. July 2021, Cytiva.

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