The importance of thyroglobulin structure for thyroid hormone biosynthesis**We shared with our friend and colleague, the late Gaetano Salvatore, a long–standing interest in thyroglobulin structure, as well as a broader interest in the optimal production of thyroid hormone and its dependence on adequate iodine supply. Over the years, we frequently discussed progress in this field with him and his many co–workers. We now welcome the opportunity to review some of our investigative work in one of his favorite fields, in his honor.