Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity
Author:
Publisher
Elsevier BV
Subject
Health, Toxicology and Mutagenesis,Genetics
Reference21 articles.
1. Spontaneous mutations in the Big Blue transgenic system are primarily mouse derived;Hill;Mutat. Res. Minireviews,1999
2. Tandem-based mutations occur in mouse liver and adipose tissue preferentially as G:C to T:A transversions and accumulate with age;Buettner;Environ. Mol. Mutagen.,1999
3. Mutation frequency and specificity with age in liver, bladder and brain of lacI transgenic mice;Stuart;Genetics,2000
4. Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in newborn and old lacZ-transgenic mouse;Ono;Mutat. Res.,2000
5. p53 Wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutation in liver, spleen and brain;Nishino;Oncogene,1995
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