Semi-quantitative evaluation of genotoxic activity of chemical substances and evidence for a biological threshold of genotoxic activity

Author:

Sofuni Toshio,Hayashi Makoto,Nohmi Takehiko,Matsuoka Atsuko,Yamada Masami,Kamata Eiich

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference5 articles.

1. The Ministry of Health and Welfare, Guidelines for Toxicity Testing of Chemicals: Testing Methods for New Chemical Substances, in: Office of Environmental Chemicals Safety, Environmental Health Bureau, The Ministry of Health and Welfare (Ed.), Guidebook for Registration of New Chemical Substances, Yakugyoujihosya, Tokyo, 1995.

2. U.S.–Japan joint meeting on the toxicological characterization of environmental chemicals of mutual interest;Damstra;Environ. Health Perspect.,1990

3. New tester strains of Salmonella typhimurium lacking O6-methylguanine DNA methyltransferases and highly sensitive to mutagenic alkylating agents;Yamada;Mutat. Res.,1997

4. Genotoxicity tests for new chemicals in Germany;Broschinski;Mutat. Res.,1998

5. F.M. Carpanini (Ed.), Aneuploidy, ECETOC Monograph No. 27, European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels, 1997.

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