Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase

Author:

Varghese Joseph N,Smith Paul W,Sollis Steven L,Blick Tony J,Sahasrabudhe Anjali,McKimm-Breschkin Jennifer L,Colman Peter M

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference61 articles.

1. Genes and proteins of the influenza virus;Lamb,1989

2. Influenza virus neuraminidase: structure, antibodies, and inhibitors;Colman;Protein Sci,1994

3. The design of anti-influenza virus drugs from the X-ray molecular structure of influenza virus neuraminidase;Varghese,1997

4. Uber die enzymatische Wirkung von Influenzavirus;Klenk;Z. Physiol. Chem,1955

5. Neuraminidase: the specific enzyme of influenza virus and Vibrio cholerae;Gottschalk;Biochim. Biophys. Acta,1957

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