VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 å resolution and mutational analysis of the interface

Author:

Muller Yves A,Chen Yvonne,Christinger Hans W,Li Bing,Cunningham Brian C,Lowman Henry B,de Vos Abraham M

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference57 articles.

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2. The role of vascular endothelial growth factor in pathological angiogenesis;Ferrara;Breast Cancer Res. Treat,1995

3. Angiogenesis in cancer, vascular, rheumatoid and other disease;Folkman;Nat. Med,1995

4. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele;Carmeliet;Nature,1996

5. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene;Ferrara;Nature,1996

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