Substrate Deformation in a Hypoxanthine-Guanine Phosphoribosyltransferase Ternary Complex

Author:

Héroux Annie,White E.Lucile,Ross Larry J.,Kuzin Alexandre P.,Borhani David W.

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference47 articles.

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2. Purine metabolism in Toxoplasma gondii;Krug;J. Biol. Chem.,1989

3. Parasite enzymes as potential targets for antiparasitic chemotherapy;Wang;J. Med. Chem.,1984

4. Hypoxanthine-guanine phosphoribosyltransferase as a therapeutic target in protozoal infections;Ullman;Infect. Agents Dis.,1995

5. Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii;Naguib;Biochem. Pharmacol.,1995

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