Targeting mammalian target of rapamycin (mTOR) for health and diseases

Author:

Tsang Chi Kwan,Qi Haiyan,Liu Leroy F.,Zheng X.F. Steven

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference103 articles.

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2. Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR;Neshat;Proc. Natl. Acad. Sci. U. S. A.,2001

3. SDZ RAD, a new rapamycin derivative: synergism with cyclosporine;Schuurman;Transplantation,1997

4. mTOR-targeted therapy of cancer with rapamycin derivatives 10.1093/annonc/mdi113;Vignot;Ann. Oncol.,2005

5. Phase I, pharmacokinetic (PK), and pharmacodynamic (PD) study of AP23573, an mTOR Inhibitor, administered IV daily X 5 every other week in patients (pts) with refractory or advanced malignancies;Mita;ASCO Meeting Abstracts,2004

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