An improved model for fragment-based lead generation at AstraZeneca-Reference-Cited by-同舟云学术

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An improved model for fragment-based lead generation at AstraZeneca

Published:2016-08 Issue:8 Volume:21 Page:1272-1283
ISSN:1359-6446
Container-title:Drug Discovery Today
language:en
Short-container-title:Drug Discovery Today

Author:

Fuller Nathan,Spadola Loredana,Cowen Scott,Patel Joe,Schönherr Heike,Cao Qing,McKenzie Andrew,Edfeldt Fredrik,Rabow Al,Goodnow Robert

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference38 articles.

1. Discovering high-affinity ligands for proteins: SAR by NMR;Shuker;Science,1996

2. Discovery of potent nonpeptide inhibitors of stromelysin using SAR by NMR;Hajduk;J. Am. Chem. Soc.,1997

3. Experiences in fragment-based drug discovery;Murray;Trends Pharmacol. Sci.,2012

4. The rise of fragment-based drug discovery;Murray;Nat. Chem.,2009

5. Fragment-based lead discovery grows up;Baker;Nat. Rev. Drug Discov.,2013

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