Targeting interleukin-6 to treat neuromyelitis optica spectrum disorders: Implications from immunology, the FcRn pathway and clinical experience

Author:

Sellner JohannORCID,Sitte Harald H.,Rommer Paulus S.

Funder

Roche

Shire

Sanofi

H. Lundbeck A/S

Biogen

Rokitan

Meso Scale Diagnostics

Novartis

Cilag

Pfizer

Merck

Bristol-Myers Squibb

Sanofi Genzyme

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference115 articles.

1. Neuromyelitis spectrum disorders;Weinshenker;Mayo Clin Proc,2017

2. The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica;Lucchinetti;Brain Pathol,2014

3. Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis;Roemer;Brain,2007

4. Distribution of aquaporins 1 and 4 in the central nervous system;Rosu;Curr Health Sci J,2019

5. EFNS guidelines on diagnosis and management of neuromyelitis optica;Sellner;Eur J Neurol,2010

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