Drug discovery efforts toward inhibitors of canonical Wnt/β-catenin signaling pathway in the treatment of cancer: A composition-of-matter review (2010

Drug discovery efforts toward inhibitors of canonical Wnt/β-catenin signaling pathway in the treatment of cancer: A composition-of-matter review (2010–2020)

Published:2021-11 Issue: Volume: Page:
ISSN:1359-6446
Container-title:Drug Discovery Today
language:en
Short-container-title:Drug Discovery Today

Author:

Morris Andrew,Pagare Piyusha P.,Li Jiong,Zhang Yan

Funder

Elsa U Pardee Foundation

Virginia Commonwealth University

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference87 articles.

1. Wnt/β-catenin signaling and disease;Clevers;Cell,2012

2. Wnt/β-Catenin signaling, disease, and emerging therapeutic modalities;Nusse;Cell,2017

3. The human F box protein β-Trcp associates with the Cul1/Skp1 complex and regulates the stability of β-catenin;Latres;Oncogene,1999

4. Drosophila Tcf and Groucho interact to repress Wingless signalling activity;Cavallo;Nature,1998

5. Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation;Daniels;Nat Struct Mol Biol,2005

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