Insights into the failure of the potential, neutral myocardial imaging agent TcN-NOET: physicochemical identification of by-products and degradation species

Author:

Tisato Francesco,Bolzati Cristina,Refosco Fiorenzo,Porchia Marina,Seraglia Roberta,Carta Davide,Pasqualini Roberto

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference30 articles.

1. Bis(dithiocarbamato) nitrido technetium-99m radiopharmaceuticals: a class of neutral myocardial imaging agents;Pasqualini;J Nucl Med,1994

2. Myocardial kinetics of TcN-NOET: a neutral lipophilic complex tracer of regional myocardial blood flow;Ghezzi;J Nucl Med,1995

3. Myocardial uptake of Tc-99m-N-NOET and (TI)-T-201 during dobutamine infusion — comparison with adenosine stress;Calnon;Circulation,1999

4. Biodistribution, dosimetry, and safety of myocardial perfusion imaging agent (TcN)-Tc-99m-NOET in healthy volunteers;Vanzetto;J Nucl Med,2000

5. The effect of ischemic injury on the cardiac transport of Tc-99m N-NOET in the isolated rabbit heart;Holly;J Nucl Cardiol,1999

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