Radiosynthesis and evaluation of [11C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 1

Author:

Yanamoto Kazuhiko,Konno Fujiko,Odawara Chika,Yamasaki Tomoteru,Kawamura Kazunori,Hatori Akiko,Yui Joji,Wakizaka Hidekatsu,Nengaki Nobuki,Takei Makoto,Zhang Ming-Rong

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference29 articles.

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2. Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity;Nakanishi;Neuron,1994

3. Metabotropic glutamate 1 receptor: current concepts and perspectives;Ferraguti;Pharmacol Rev,2008

4. A novel class of antagonists for metabotropic glutamate receptors, 7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxylates;Annoura;Bioorg Med Chem Lett,1996

5. CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding;Litschig;Mol Pharmacol,1999

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