Engineering an antibody with picomolar affinity to DOTA chelates of multiple radionuclides for pretargeted radioimmunotherapy and imaging

Author:

Orcutt Kelly Davis,Slusarczyk Adrian L.,Cieslewicz Maryelise,Ruiz-Yi Benjamin,Bhushan Kumar R.,Frangioni John V.,Wittrup K. Dane

Funder

National Institutes of Health

National Science Foundation Graduate Research Fellowship to K.D.O.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Molecular Medicine

Reference56 articles.

1. Cure of human carcinoma xenografts by a single dose of pretargeted yttrium-90 with negligible toxicity;Axworthy;Proc Natl Acad Sci USA,2000

2. Cancer Imaging and Therapy with Bispecific Antibody Pretargeting;Goldenberg;Update Cancer Ther,2007

3. Pharmacokinetics of pretargeted monoclonal-antibody 2d12.5 and Y-88 Janus-2-(P-nitrobenzyl)-1,4,7,10-tetraazacyclododecanetetraacetic acid (DOTA) in Balb/C mice with Khjj mouse adenocarcinoma — a model for Y-90 radioimmunotherapy;Goodwin;Cancer Res,1994

4. Successful radiotherapy of tumor in pretargeted mice by 188Re-radiolabeled phosphorodiamidate morpholino oligomer, a synthetic DNA analogue;Liu;Clin Cancer Res,2006

5. Comparative biodistributions of pretargeted radioimmunoconjugates targeting CD20, CD22, and DR molecules on human B-cell lymphomas;Pantelias;Blood,2007

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